DB07107

552332-71-5

Akt, Bcr-Abl

Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Angiogenesis

DB07107 is a potent inhibitor of drug resistant T315I mutant Bcr-Abl tyrosine kinase and a potent Akt1 inhibitor (IC50: 360 nM) .

C([C@H](COC=1C=C(/C=C/C=2C=CN=CC2)C=NC1)N)C=3C=4C(NC3)=CC=CC4

C23H22N4O

370.45

Ice Packs

-20°C