D5D-IN-326
Product Specifications
CAS Number
1236767-85-3
Target
Others, Stearoyl-CoA Desaturase (SCD)
Related Pathways
Others, Metabolism
Bioactivity
D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays) . It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice.
Smiles
FC(F)(F)COc1ccc(cc1)-n1c(OCC(F)(F)C(F)(F)F)nc2NC(=O)Cc2c1=O
Molecular Formula
C17H11F8N3O4
Molecular Weight
473.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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