Momelotinib sulfate

1056636-06-6

Apoptosis, Autophagy, JAK

Tyrosine Kinase/Adaptors, Autophagy, Angiogenesis, Chromatin/Epigenetic, Stem Cells, Apoptosis, JAK/STAT signaling

Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM) . It has 10-fold selectivity versus JAK3.

OS(O)(=O)=O.OS(O)(=O)=O.O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

C23H26N6O10S2

610.62

Ice Packs

-20°C