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Momelotinib sulfate

Product Specifications

CAS Number

1056636-06-6

Target

Apoptosis|||Autophagy|||JAK

Related Pathways

Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic|||Stem Cells|||Apoptosis|||JAK/STAT signaling

Bioactivity

Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM) . It has 10-fold selectivity versus JAK3.

Smiles

OS(O)(=O)=O.OS(O)(=O)=O.O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

Molecular Formula

C23H26N6O10S2

Molecular Weight

610.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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