Momelotinib sulfate
Product Specifications
CAS Number
1056636-06-6
Target
Apoptosis|||Autophagy|||JAK
Related Pathways
Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic|||Stem Cells|||Apoptosis|||JAK/STAT signaling
Bioactivity
Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM) . It has 10-fold selectivity versus JAK3.
Smiles
OS(O)(=O)=O.OS(O)(=O)=O.O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
Molecular Formula
C23H26N6O10S2
Molecular Weight
610.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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