Momelotinib Mesylate
Product Specifications
CAS Number
1056636-07-7
Target
Autophagy, JAK
Related Pathways
Angiogenesis, Stem Cells, Autophagy, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
Bioactivity
Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM) . It has 10-fold selectivity versus JAK3.
Smiles
CS(O)(=O)=O.O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
Molecular Formula
C24H26N6O5S
Molecular Weight
510.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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