CUR61414 hydrochloride
Product Specifications
Target
Hedgehog/Smoothened
Related Pathways
GPCR/G Protein|||Stem Cells
Purity
0.9522
Bioactivity
CUR61414 hydrochloride is a potent and cell permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) . CUR61414 hydrochloride is a small-molecule aminoproline class compound. CUR61414 hydrochloride selectively binds to smoothened (Smo, Ki= 44 nM) . CUR61414 hydrochloride can induce cancer cells apoptosis without affecting neighboring non-tumor cells.
Smiles
Cl.COc1cccc(CN([C@H]2C[C@H](N(Cc3ccc4OCOc4c3)C2)C(=O)N2CCNCC2)C(=O)CC(C)(C)C)c1
Molecular Formula
C31H43ClN4O5
Molecular Weight
587.15
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/95EF325D-CE8E-4552-8F50-A34D643EEFCD/T15019L
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS711390-01 0.1 mL
Rabbit anti-human CDGSH iron sulfur domain 1 polyclonal Antibody
Ask
View Details 
MBS711390-02 5x 0.1 mL
Rabbit anti-human CDGSH iron sulfur domain 1 polyclonal Antibody
Ask
View Details 
GTR15144109 1 Vial
Lentiviral mouse Hrh1 shRNA (UAS) - Lentiviral mouse Hrh1 shRNA (UAS, RFP) plasmid
Ask
View Details