CUR61414
Product Specifications
CAS Number
334998-36-6
Target
Smo, Hedgehog/Smoothened, Apoptosis
Related Pathways
Stem Cells, GPCR/G Protein, Apoptosis
Purity
0.98
Bioactivity
CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM) .
Smiles
COc1cccc(CN([C@H]2C[C@H](N(Cc3ccc4OCOc4c3)C2)C(=O)N2CCNCC2)C(=O)CC(C)(C)C)c1
Molecular Formula
C31H42N4O5
Molecular Weight
550.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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