CJ-42794
Product Specifications
CAS Number
847728-01-2
Target
Others, Prostaglandin Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Others
Purity
0.9992
Bioactivity
CJ-42794 (CJ-042794) is a selective antagonist of the prostaglandin E receptor subtype 4 (EP4), inhibiting [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It exhibits a binding affinity that is at least 200-fold more selective for the human EP4 receptor than for other human EP receptor subtypes (EP1, EP2, and EP3) (IC50: 8.5 (pKi) ) .
Smiles
C[C@H](NC(=O)c1cc(Cl)ccc1Oc1ccc(F)cc1)c1ccc(cc1)C(O)=O
Molecular Formula
C22H17ClFNO4
Molecular Weight
413.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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