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Ciliobrevin D

Product Specifications

CAS Number

1370554-01-0

Target

ATPase, Hedgehog/Smoothened

Related Pathways

Stem Cells, Membrane transporter/Ion channel, GPCR/G Protein

Purity

>99.99%

Bioactivity

Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity in vitro.

Smiles

Clc1ccc(C(=O)C(\C#N)=C2/NC(=O)c3ccc(Cl)cc3N2)c(Cl)c1

Molecular Formula

C17H8Cl3N3O2

Molecular Weight

392.62

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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