Ciliobrevin D
Product Specifications
CAS Number
1370554-01-0
Target
ATPase, Hedgehog/Smoothened
Related Pathways
Stem Cells, Membrane transporter/Ion channel, GPCR/G Protein
Purity
>99.99%
Bioactivity
Ciliobrevin D is a AAA+ ATPase motor cytoplasmic dynein inhibitor. Ciliobrevin D inhibits Hedgehog (Hh) signaling and primary cilia formation and it also inhibits dynein-dependent microtubule gliding and ATPase activity in vitro.
Smiles
Clc1ccc(C(=O)C(\C#N)=C2/NC(=O)c3ccc(Cl)cc3N2)c(Cl)c1
Molecular Formula
C17H8Cl3N3O2
Molecular Weight
392.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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