CH-0793076
Product Specifications
CAS Number
534605-78-2
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
CH-0793076, a hexacyclic camptothecin analog, is an active drug and major metabolite of TP300. CH-0793076 is efficacious against cells expressing BCRP (breast cancer resistance protein) . CH-0793076 inhibits DNA topoisomerase I (IC50: 2.3 μM) .
Smiles
C(CCCC)N1C=2C=3C(N=C4C2CN5C4=CC6=C(C5=O)COC(=O)[C@@]6(CC)O)=CC=CC3N=C1
Molecular Formula
C26H26N4O4
Molecular Weight
458.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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