Elexacaftor
Product Specifications
CAS Number
2216712-66-0
Target
Autophagy, CFTR
Related Pathways
Autophagy, Membrane transporter/Ion channel
Purity
0.9987
Bioactivity
Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It promotes the processing and trafficking of CFTR, increases the amount of CFTR on the cell surface, and improves the processing and trafficking of Phe508del CFTR protein.
Smiles
C(NS(=O)(=O)C1=CN(C)N=C1C)(=O)C2=C(N=C(C=C2)N3N=C(OCC(C(F)(F)F)(C)C)C=C3)N4C[C@@H](C)CC4(C)C
Molecular Formula
C26H34F3N7O4S
Molecular Weight
597.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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