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CE-245677

Product Specifications

CAS Number

717899-97-3

Target

Tie-2, Trk receptor

Related Pathways

Tyrosine Kinase/Adaptors

Purity

0.9923

Bioactivity

CE-245677 is a potent, reversible inhibitor of Tie2 and TrkA/B kinases, with cellular IC50 values of 4.7 nM and 1 nM, respectively.

Smiles

COc1ccc(cc1NC(=O)Nc1ccc(Cl)cc1Cl)C(=O)c1cn(C(C)C)c2ncnc(N)c12

Molecular Formula

C24H22Cl2N6O3

Molecular Weight

513.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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