CC0651
Product Specifications
CAS Number
1319207-44-7
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Purity
0.9903
Bioactivity
CC0651 is a highly selective allosteric inhibitor of human Cdc34 ubiquitin-conjugating enzyme (UCE), inhibiting p27 Kip1 ubiquitination (IC50=1.72 μM) by blocking ubiquitin transfer to substrates, for use in cancer research.
Smiles
COCC(=O)N[C@@H](Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1)[C@H](O)[C@@H](O)C(O)=O
Molecular Formula
C20H21Cl2NO6
Molecular Weight
442.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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