CBS9106
Product Specifications
CAS Number
1076235-04-5
Target
CRM1|||Apoptosis
Related Pathways
Apoptosis|||Membrane transporter/Ion channel
Purity
0.9909
Bioactivity
CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activity.CBS9106 inhibits CRM1-dependent nuclear export and reduces CRM1 protein levels.CBS9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.CBS9106 is an inhibitor of CRM1-dependent nuclear export and reduces CRM1 protein levels.
Smiles
O=C1C(=C(C(=O)N1NC2=NC(Cl)=C(C=C2)C(F)(F)F)COCCC(C)(C)C)C
Molecular Formula
C18H21ClF3N3O3
Molecular Weight
419.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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