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CAY10566

Product Specifications

CAS Number

944808-88-2

Target

Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

Related Pathways

Metabolism

Purity

0.9954

Bioactivity

CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM) . CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively..

Smiles

Cc1nnc(o1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)ccc1Cl

Molecular Formula

C18H17ClFN5O2

Molecular Weight

389.81

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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