CAY10566
Product Specifications
CAS Number
944808-88-2
Target
Dehydrogenase|||Stearoyl-CoA Desaturase (SCD)
Related Pathways
Metabolism
Purity
0.9954
Bioactivity
CAY10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM) . CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively..
Smiles
Cc1nnc(o1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)ccc1Cl
Molecular Formula
C18H17ClFN5O2
Molecular Weight
389.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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