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Carboxyamidotriazole Orotate

Product Specifications

CAS Number

187739-60-2

Target

Calcium Channel

Related Pathways

Membrane transporter/Ion channel|||Metabolism

Purity

0.9988

Bioactivity

Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and associated signaling pathways. As the orotate salt form of Carboxyamidotriazole (CAI), it is an orally bioavailable signal transduction inhibitor with in vitro antileukaemic activity, exhibiting anti-tumor, anti-inflammatory, and antiangiogenic effects.

Smiles

OC(=O)c1cc(=O)[nH]c(=O)[nH]1.NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N

Molecular Formula

C22H16Cl3N7O6

Molecular Weight

580.76

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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