Calicheamicin
Product Specifications
CAS Number
108212-75-5
Target
DNA Alkylator/Crosslinker, Apoptosis, ADC Cytotoxin, Antibacterial, Antibiotic
Related Pathways
Microbiology/Virology, Apoptosis, Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Purity
0.9878
Bioactivity
Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.
Smiles
[H][C@@]1(C[C@H](OC)[C@H](CO1)NCC)O[C@@H]1[C@@H](O)[C@H](NO[C@H]2C[C@H](O)[C@H](SC(=O)c3c(C)c(I)c(O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](OC)[C@H]4O)c(OC)c3OC)[C@@H](C)O2)[C@@H](C)O[C@@]1([H])O[C@H]1C#C\C=C/C#C[C@]2(O)CC(=O)C(NC(=O)OC)=C1\C2=C\CSSSC
Molecular Formula
C55H74IN3O21S4
Molecular Weight
1368.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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