BRD5529
Product Specifications
CAS Number
1358488-78-4
Target
Others, E1/E2/E3 Enzyme
Related Pathways
Others, Ubiquitination
Bioactivity
BRD5529 is a selective inhibitor of CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction (IC50: 8.6 μM) . BRD5529 directly and selectively binds CARD9, disrupts TRIM62 recruitment, inhibits TRIM62-mediated ubiquitinylation, and activation of CARD9.
Smiles
Cc1ccc(cc1)C(=O)Nc1cnc(N2CCC(CC2)(N2CCCCC2)C(N)=O)c(c1)C(O)=O
Molecular Formula
C25H31N5O4
Molecular Weight
465.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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