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Exatecan Intermediate 4 (dihydrochloride)

Product Specifications

UNSPSC Description

Exatecan Intermediate 4 dihydrochloride is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers[1][2].

Target Antigen

ADC Cytotoxin; Topoisomerase

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/exatecan-intermediate-4-dihydrochloride.html

Purity

99.92

Solubility

DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

[H]Cl.[H]Cl.CC1=C2CCC(C(C2=C(C=C1F)N)=O)N

Molecular Weight

281.15

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W021377C/Exatecan-Intermediate-4-dihydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W021377C/Exatecan-Intermediate-4-dihydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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