BN201
Product Specifications
CAS Number
1361200-34-1
Target
Others, FOXO, SGK, IGF-1R
Related Pathways
Others, Tyrosine Kinase/Adaptors, Apoptosis, Metabolism
Purity
0.9973
Bioactivity
BN201 (OCS-05) is a drug with neuroprotective and myelin repair effects, which acts mainly by activating serum glucocorticoid kinase-2 (SGK2), which in turn activates the FOXO3 pathway to promote neuronal survival and myelin repair. It is mainly used for the treatment of inflammatory neurological diseases such as multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE) .BN201 is able to regulate multiple kinases in the insulin growth factor 1 (IGF1) pathway and cross the blood-brain barrier.
Smiles
O=C(N)CN(C(=O)CN(C(=O)CNCCC=1C=CC=CC1F)CC(C)C)CCCN2C(=O)CCC2
Molecular Formula
C25H38FN5O4
Molecular Weight
491.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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