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BMX-IN-1

Product Specifications

CAS Number

1431525-23-3

Target

BTK

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9838

Bioactivity

BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton's tyrosine kinase (BTK, IC50 = 10.4 nM), but BMX-IN-1 is more than 47-656 fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

Smiles

Cc1ccc(cc1NC(=O)C=C)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1ccc(NS(C)(=O)=O)cc1

Molecular Formula

C29H24N4O4S

Molecular Weight

524.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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