BMT-090605
Product Specifications
CAS Number
1551403-51-0
Target
Serine/threonin kinase, AAK1 (AP2 associated kinase 1), Others
Related Pathways
Others, Cell Cycle/Checkpoint, Metabolism, Neuroscience
Bioactivity
BMT-090605 is a potent, selective AAK1 inhibitor with an IC50 of 0.6 nM, and inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 also exhibits antinociceptive activity.
Smiles
CN1C=2C(C=3C(C1=O)=C(C)N=CC3)=CC(C#N)=C(OC[C@H](CC(C)C)N)C2
Molecular Formula
C21H24N4O2
Molecular Weight
364.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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