BMS-986163
Product Specifications
CAS Number
1801151-09-6
Target
NMDAR
Related Pathways
Neuroscience
Bioactivity
BMS-986163 is an effective GluN2B negative allosteric modulator prodrug that converts to the active form BMS-986169 (Ki=4 nM, IC50=24 nM) in vivo, exhibiting antidepressant-like activity in mice.
Smiles
O=C1[C@@H](CCN1CC2=CC=C(C)C=C2)N3C[C@@H](F)[C@@H](CC3)C4=CC=C(OP(=O)(O)O)C=C4
Molecular Formula
C23H28FN2O5P
Molecular Weight
462.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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