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BMS-986163

Product Specifications

CAS Number

1801151-09-6

Target

NMDAR

Related Pathways

Neuroscience

Bioactivity

BMS-986163 is an effective GluN2B negative allosteric modulator prodrug that converts to the active form BMS-986169 (Ki=4 nM, IC50=24 nM) in vivo, exhibiting antidepressant-like activity in mice.

Smiles

O=C1[C@@H](CCN1CC2=CC=C(C)C=C2)N3C[C@@H](F)[C@@H](CC3)C4=CC=C(OP(=O)(O)O)C=C4

Molecular Formula

C23H28FN2O5P

Molecular Weight

462.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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