BMS-690514
Product Specifications
CAS Number
859853-30-8
Target
VEGFR, EGFR, HER
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Purity
0.9908
Bioactivity
BMS-690514 is a potent, orally active inhibitor of EGFR and VEGFR, with IC50 values of 5 nM for EGFR, 20 nM for HER 2, and 60 nM for HER 4.
Smiles
COc1cccc(Nc2ncnn3ccc(CN4CC[C@@H](N)[C@H](O)C4)c23)c1
Molecular Formula
C19H24N6O2
Molecular Weight
368.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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