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BMS-690514

Product Specifications

CAS Number

859853-30-8

Target

VEGFR|||EGFR|||HER

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Purity

0.9908

Bioactivity

BMS-690514 is a potent, orally active inhibitor of EGFR and VEGFR, with IC50 values of 5 nM for EGFR, 20 nM for HER 2, and 60 nM for HER 4.

Smiles

COc1cccc(Nc2ncnn3ccc(CN4CC[C@@H](N)[C@H](O)C4)c23)c1

Molecular Formula

C19H24N6O2

Molecular Weight

368.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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