BMS-248360
Product Specifications
CAS Number
254737-87-6
Target
Endothelin Receptor, RAAS, Others
Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Others
Bioactivity
BMS-248360 is a potent, orally active dual antagonist of both angiotensin II receptor (AT1) and endothelin A (ETA) receptor, with Kis of 10 nM and 1.9 nM for hAT1 and hETA receptors, respectively. BMS-248360 demonstrates hypertensive effects[1].
Smiles
O=C1C2(N=C(CCCC)N1CC3=CC(CN4C(=O)C(C)(C)CC4)=C(C=C3)C5=C(S(NC6=C(C)C(C)=NO6)(=O)=O)C=CC=C5)CCCC2
Molecular Formula
C36H45N5O5S
Molecular Weight
659.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
F8262 96 Tests
Phosphate carrier protein mitochondrial (SLC25A3) Rat ELISA Kit
Sign In for Pricing
View Details 
130760-HRP 100 µL
Osteopontin (Bone Sialoprotein 1, Nephropontin, Secreted Phosphoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, SPP1, BNSP, OPN, PSEC0156, MGC110940) (HRP)
Sign In for Pricing
View Details