BMS-1166 hydrochloride
Product Specifications
CAS Number
2113650-05-6
Target
PD-1/PD-L1, Others
Related Pathways
Apoptosis, Immunology/Inflammation, Others, Cell Cycle/Checkpoint
Bioactivity
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM) . BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM) . BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Smiles
Cl.Cc1c(COc2cc(OCc3cccc(c3)C#N)c(CN3C[C@H](O)C[C@@H]3C(O)=O)cc2Cl)cccc1-c1ccc2OCCOc2c1
Molecular Formula
C36H34Cl2N2O7
Molecular Weight
677.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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