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BI8626

Product Specifications

CAS Number

1875036-75-1

Target

E1/E2/E3 Enzyme

Related Pathways

Ubiquitination

Purity

0.9984

Bioactivity

BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells.

Smiles

NCc1cccc(CNc2ncnc3c(ncnc23)N2CCN(Cc3ccccc3)CC2)c1

Molecular Formula

C25H28N8

Molecular Weight

440.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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