BI8626
Product Specifications
CAS Number
1875036-75-1
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Purity
0.9984
Bioactivity
BI8626 is a ubiquitin ligase HUWE1 inhibitor with protective effects against spontaneous desiccation syndrome in NOD/ShiLtj mice.BI8626 inhibits intracellular cholesterol and decreases the expression of phosphorylated ZAP-70, CD25, and other activation markers, and inhibits the proliferation of CD4 T-cells.
Smiles
NCc1cccc(CNc2ncnc3c(ncnc23)N2CCN(Cc3ccccc3)CC2)c1
Molecular Formula
C25H28N8
Molecular Weight
440.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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