BI8622
Product Specifications
CAS Number
1875036-74-0
Target
DNA/RNA Synthesis, E1/E2/E3 Enzyme, c-Myc
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9828
Bioactivity
BI8622 is a ubiquitin ligase HUWE1-specific antagonist that restores the level of RP2 mutants in retinal cell lines and inhibits the activation of NLRP3, NLRC4, and AIM2 inflammatory vesicles in cells.
Smiles
N#CC1(C=2C=CC=CC2)CCN(C=3N=CN=C(C(=O)NC4=CC=C(C=C4)CN)C3C)CC1
Molecular Formula
C25H26N6O
Molecular Weight
426.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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