JWG-071
Product Specifications
CAS Number
2250323-50-1
Target
Epigenetic Reader Domain, ERK
Related Pathways
MAPK, Chromatin/Epigenetic
Purity
0.9983
Bioactivity
JWG-071, the first reported chemical probe for ERK5 kinase selectivity, is a BET-selective inhibitor with a 1 μM BRD4 IC that enhances both ERK5 activity and BRD4 selectivity.
Smiles
CCC(C)N1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(cc3OC)C(=O)N3CCC(CC3)N3CCN(C)CC3)nc12
Molecular Formula
C34H44N8O3
Molecular Weight
612.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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