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JWG-071

Product Specifications

CAS Number

2250323-50-1

Target

Epigenetic Reader Domain, ERK

Related Pathways

MAPK, Chromatin/Epigenetic

Purity

0.9983

Bioactivity

JWG-071, the first reported chemical probe for ERK5 kinase selectivity, is a BET-selective inhibitor with a 1 μM BRD4 IC that enhances both ERK5 activity and BRD4 selectivity.

Smiles

CCC(C)N1c2ccccc2C(=O)N(C)c2cnc(Nc3ccc(cc3OC)C(=O)N3CCC(CC3)N3CCN(C)CC3)nc12

Molecular Formula

C34H44N8O3

Molecular Weight

612.77

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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