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Axitinib

Product Specifications

CAS Number

319460-85-0

Target

PDGFR, VEGFR, c-Kit

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9981

Bioactivity

Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1, VEGFR2, VEGFR3, and PDGFRβ (IC50=4/20/0.4/2 nM) . Axitinib has antitumor activity and is used in the treatment of renal cell carcinoma.

Smiles

C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2

Molecular Formula

C22H18N4OS

Molecular Weight

386.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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