Axitinib
Product Specifications
CAS Number
319460-85-0
Target
PDGFR, VEGFR, c-Kit
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9981
Bioactivity
Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1, VEGFR2, VEGFR3, and PDGFRβ (IC50=4/20/0.4/2 nM) . Axitinib has antitumor activity and is used in the treatment of renal cell carcinoma.
Smiles
C(=C/C1=CC=CC=N1)\C=2C=3C(=CC(SC4=C(C(NC)=O)C=CC=C4)=CC3)NN2
Molecular Formula
C22H18N4OS
Molecular Weight
386.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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