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AZD5582 acetate (1258392-53-8 free base)

Product Specifications

Target

IAP

Related Pathways

Apoptosis

Purity

0.9776

Bioactivity

AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis.

Smiles

C[C@H](NC)C(N[C@H](C(N1CCC[C@H]1C(N[C@@H]2[C@H](OCC#CC#CCO[C@@H]3CC4=CC=CC=C4[C@@H]3NC([C@@H]5CCCN5C([C@@H](NC([C@@H](NC)C)=O)C6CCCCC6)=O)=O)CC7=CC=CC=C27)=O)=O)C8CCCCC8)=O.CC(O)=O

Molecular Formula

C60H82N8O10

Molecular Weight

1075.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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