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AZD4320

Product Specifications

CAS Number

1357576-48-7

Target

Bcl-2 Family

Related Pathways

Apoptosis

Purity

0.9971

Bioactivity

AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively.

Smiles

CN(CCO)CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)[C@@H](O)c1ccccc1-c1ccc(Cl)cc1

Molecular Formula

C45H48ClF3N4O7S3

Molecular Weight

945.53

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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