AZD2906
Product Specifications
CAS Number
1034148-15-6
Target
Glucocorticoid Receptor, Others
Related Pathways
Endocrinology/Hormones, Others
Bioactivity
AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.
Smiles
COc1ccc(cn1)[C@@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)[C@H](C)NC(=O)C1CC1
Molecular Formula
C26H25FN4O3
Molecular Weight
460.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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