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AZD2906

Product Specifications

CAS Number

1034148-15-6

Target

Glucocorticoid Receptor, Others

Related Pathways

Endocrinology/Hormones, Others

Bioactivity

AZD2906, a selective glucocorticoid receptor (GR) agonist, demonstrates inhibitory concentrations (IC50s) of 2.2 nM in human GR, 0.3 nM in rat peripheral blood mononuclear cells (PBMC), 41.6 nM in human whole blood, and 7.5 nM in rat whole blood, respectively[1]. Additionally, it induces an increase in micronucleated immature erythrocytes within rat bone marrow.

Smiles

COc1ccc(cn1)[C@@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)[C@H](C)NC(=O)C1CC1

Molecular Formula

C26H25FN4O3

Molecular Weight

460.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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