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AZD2423

Product Specifications

CAS Number

1229603-37-5

Target

CCR

Related Pathways

Microbiology/Virology, GPCR/G Protein, Immunology/Inflammation

Bioactivity

AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator with an IC50 of 1.2 nM for CCR2 Ca2+ flux [1][2][3].

Smiles

CC(C)(C)N1CCN[C@H](C1)C(=O)N1CCN(CC1)C(=O)Nc1ccc(Cl)c(F)c1

Molecular Formula

C20H29ClFN5O2

Molecular Weight

425.93

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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