AZ-23
Product Specifications
CAS Number
915720-21-7
Target
Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.994
Bioactivity
AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.
Smiles
CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)ncc2Cl)n[nH]1
Molecular Formula
C17H19ClFN7O
Molecular Weight
391.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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