Spebrutinib besylate
Product Specifications
CAS Number
1360053-81-1
Target
BTK
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor with an IC50 of less than 0.5 nM and a Kinact/Ki of 7.69x10^4 M^-1s^-1.
Smiles
O=C(C=C)NC1=CC=CC(=C1)NC2=NC(=NC=C2F)NC3=CC=C(OCCOC)C=C3.O=S(=O)(O)C=1C=CC=CC1
Molecular Formula
C28H28FN5O6S
Molecular Weight
581.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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