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Spebrutinib besylate

Product Specifications

CAS Number

1360053-81-1

Target

BTK

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis

Bioactivity

Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor with an IC50 of less than 0.5 nM and a Kinact/Ki of 7.69x10^4 M^-1s^-1.

Smiles

O=C(C=C)NC1=CC=CC(=C1)NC2=NC(=NC=C2F)NC3=CC=C(OCCOC)C=C3.O=S(=O)(O)C=1C=CC=CC1

Molecular Formula

C28H28FN5O6S

Molecular Weight

581.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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