Aumitin
Product Specifications
CAS Number
946293-78-3
Target
Autophagy
Related Pathways
Autophagy
Purity
0.9913
Bioactivity
Aumitin, a diaminopyrimidine-based autophagy inhibitor, dose-dependently inhibits starvation- and rapamycin-induced autophagy with IC50s of 0.12 μM and 0.24 μM, respectively [1], and also inhibits mitochondrial respiration by targeting complex I.
Smiles
Cc1cc(Nc2ccccc2)nc(Nc2ccc(NC(=O)c3ccccc3Cl)cc2)n1
Molecular Formula
C24H20ClN5O
Molecular Weight
429.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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