Aumitin

Product Specifications

CAS Number

946293-78-3

Target

Autophagy

Related Pathways

Autophagy

Purity

0.9913

Bioactivity

Aumitin, a diaminopyrimidine-based autophagy inhibitor, dose-dependently inhibits starvation- and rapamycin-induced autophagy with IC50s of 0.12 ?M and 0.24 ?M, respectively [1], and also inhibits mitochondrial respiration by targeting complex I.

Smiles

Cc1cc(Nc2ccccc2)nc(Nc2ccc(NC(=O)c3ccccc3Cl)cc2)n1

Molecular Formula

C24H20ClN5O

Molecular Weight

429.9

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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