Atabecestat
Product Specifications
CAS Number
1200493-78-2
Target
BACE, Beta-Secretase
Related Pathways
Neuroscience
Purity
0.9977
Bioactivity
Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Aβ reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1].
Smiles
C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
Molecular Formula
C18H14FN5OS
Molecular Weight
367.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15290125 1 Vial
Lentiviral mouse Slc39a2 shRNA (UAS) - Lentiviral mouse Slc39a2 shRNA (UAS, RFP) plasmid
Sign In for Pricing
View Details 
038829-ML490 100 µL
NCK1, NT (NCK1, NCK, Cytoplasmic protein NCK1, NCK adaptor protein 1, SH2/SH3 adaptor protein NCK-alpha) (MaxLight 490) discontinued
Sign In for Pricing
View Details MBS7251735-01 48 Well
Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D) ELISA Kit
Sign In for Pricing
View Details MBS7251735-02 96 Well
Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D) ELISA Kit
Sign In for Pricing
View Details MBS7251735-03 5x 96 Well
Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D) ELISA Kit
Sign In for Pricing
View Details MBS7251735-04 10x 96 Well
Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D) ELISA Kit
Sign In for Pricing
View Details