Rimiducid
Product Specifications
CAS Number
195514-63-7
Target
Apoptosis, FKBP, Fatty Acid Synthase
Related Pathways
Autophagy, Apoptosis, Metabolism, Immunology/Inflammation
Purity
0.9954
Bioactivity
Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding to wild-type fkbp12 with 1000-fold lower affinity. Rimiducid is a dimerizer agent that acts by cross-linking the FKBP domains. It dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis.
Smiles
CC[C@H](C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccc(OC)c(OC)c1)c1cccc(OCC(=O)NCCNC(=O)COc2cccc(c2)[C@@H](CCc2ccc(OC)c(OC)c2)OC(=O)[C@@H]2CCCCN2C(=O)[C@@H](CC)c2cc(OC)c(OC)c(OC)c2)c1)c1cc(OC)c(OC)c(OC)c1
Molecular Formula
C78H98N4O20
Molecular Weight
1411.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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